منابع مشابه
Biology and biogenesis of shed microvesicles
The ability of cells to transmit bioactive molecules to recipient cells and the extracellular environment is a fundamental requirement for both normal physiology and disease pathogenesis. It has traditionally been thought that soluble factors released from cells were responsible for this cellular signaling but recent research has revealed a fundamental role for microvesicles in this process. Mi...
متن کاملExtracellular vesicles: Exosomes, microvesicles, and friends
Cells release into the extracellular environment diverse types of membrane vesicles of endosomal and plasma membrane origin called exosomes and microvesicles, respectively. These extracellular vesicles (EVs) represent an important mode of intercellular communication by serving as vehicles for transfer between cells of membrane and cytosolic proteins, lipids, and RNA. Deficiencies in our knowled...
متن کاملThe Yin–Yang of Microvesicles (Exosomes) in Cancer Biology
Microvesicles and exosomes have emerged as a new mode of intercellular communication in cancer. In recent years, microvesicles have received increasing attention from the scientific community for their role in regulating and transferring active molecules responsible for tumor progression and metastasis. Controversy arises from the fact that microvesicles can transfer tumor-promoting molecules s...
متن کاملMicrovesicles: mediators of extracellular communication during cancer progression.
Microvesicles are generated by the outward budding and fission of membrane vesicles from the cell surface. Recent studies suggest that microvesicle shedding is a highly regulated process that occurs in a spectrum of cell types and, more frequently, in tumor cells. Microvesicles have been widely detected in various biological fluids including peripheral blood, urine and ascitic fluids, and their...
متن کاملEpididymosomes: Role of extracellular microvesicles in sperm maturation.
The spermatozoa of vertebrate species that practice internal fertilization have to transit along the epididymis after leaving the testis. This epididymis is a single, long convoluted tubule that links the testis to the vas deferens (1). During this transit, the male gametes acquire their fertilizing ability and their forward motility properties. Collectively, these modifications known as sperm ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Traffic
سال: 2018
ISSN: 1398-9219
DOI: 10.1111/tra.12558